chitosan

Der Sommer neigt sich zum Ende – das heißt aber nicht, dass die News rund um Chitosan nicht heiß sind. Hier der Review der Chitosan Veröffentlichungen im August. 97 wissenschaftliche Artikel wurden veröffentlicht, in denen mit Chitosan gearbeitet wurde. Im Int J Biol Macromol wurden 8 Artikel veröffentlicht. Die Top drei Nationen bezogen auf die Anzahl der Artikel sind China, USA und Indien, gefolgt von Portugal auf Platz 4.

In July several outstanding articles about chitosan had been published around the world.  All in all 122 articles were released in 67 different journals. With regard to the number of publications the leading countries are China (31), the USA (20) and South Korea (10).

Youngnam Cho and Richard Borgens of the Purdue University in West Lafayette, USA found, what researchers were looking for since many years: a medium to medicate damaged nerve cells in the spinal cord. Chitosan is the new white hope in research and for concerned persons.

Organic farming products are very popular. Scientists discover why they are savory. The polymer chitosan may activate natural mechanisms that intensify the taste of plants or their fruit.

Biotechnology company is awarded with the “Best Early Stage Company” Award of the New Jersey Technology Councils (NJTC) and leaves other companies from life sciences, information technology, energy/environmental management, telecommunications and nanotechnology behind.

How can ecology and sustainability be combined with cleaning agents? What is the role of chitosan?

This year again students run experiments with chitosan. Johannes W. at the secondary school “Gymnasium Oberalster” in Hamburg produced biodegradable films containing chitin or chitosan.

Researchers at the University of Washington in Seattle, USA designed a promising novel three-dimensional scaffold for stem cells. Main ingredients are chitosan and alginate.

Scientists at the Basque technological centre Neiker-Tecnalia tested chitosan as a healthy alternative to prohibited, growth-promoting antibiotics for ruminants.

Scientists of the University of Hamburg investigated the activity of chitosan against four microorganisms that can be found especially in seafood.

Since December 2009 Heppe Medical Chitosan GmbH is patron of the words chitin and chitosan. Word patrons commit to protect their words, to use them carefully, to preserve them and to enhance their application.

Even in the beginning of summer chitin and chitosan research is going on. 130 articles were published in journals. 50 submitted papers edited in China, 10 in the US and 9 in South Corea. You want to learn more about the foci of interest? Just keep on reading.

Besides the event in the first half of the year 2009 - the European Conference on Chitin and Chitosan in Venice - many different articles in chitin and chitosan research were published in scientific journals. Here you can find an overview of some of them...

Whats new in April? Many different articles about chitin and chitosan were published in scientific journals.

The younth in Germany is also researching about chitosan. Two scoolgirls land not only a first prize, but also a special prize on regional as well as on state level  of the competition "Jugend forscht". Title of their work: Biopolymer, Lipidabsorber, Ion exchanger, anti microbial agent: The allrounder Chitosan.

Chitosan is employed in many domains. Besides medical areas like e.g. as support in wound healing or in tissue engineering chitosan can also be applied in the fields of food technology and water management. Thanks to scientists of the faculty of Microsystems Technic at the Univesity of Stuttgart, chitosan might soon become part of biocompatible fuel cells.

Scientist at the Mississippi South University in Hattiesburg succeded a spectacular development - a self-reparing material when exposed to ultraviolet light. Prof. Marek Urban and Ph.D. student Biswajit Ghosh were researching on a coating, which main components are chitosan and oxetan. From their point of view this priniciple can be of greatest importance for many matrials.

In the first two months of this year numerous articles about chitosannanoparticles has been published into the following journals: biomaterials [6],  biomed mater res a [2], j mater sci-mater m [2], langmuir [2], biomacromolecules [2]. The Authors are from Asia, Europe and Northamerica.

In the first two months of the year articles were published predominantly in these journals: biomaterials [6], biomed mater res a [2], j mater sci-mater m [2], langmuir [2], biomacromolecultes [2] Authors are from Asia, Europe and Northamerica. The treated topics are presented in this article. The data was obtained through GoPubMed.

150 Years ago C. Rouget discovered the biopolymer chitosan when cooking chitin in a base. Ever since, the interest in this polymer is increasing constantly. On the one hand new application fields are developed over and over again. On the other hand the primary material chitin is a renewable resource, which is generated as by-product in huge annual quantities in food-industry.

Chitosan - NanoBioSaccharides brightens up the darkNanoBioSaccharides - a project that aimed to unravel the properties of an apparent panacea is now concluded. During the last three years over 600 researchers from seven nations, managed by Prof. Dr. Bruno Moerschbacher of the University of Muenster dedicated their time to study the striking abilities of Chitosan and its application in human medicine. In Nanobiotechnology a breakthrough is expected, that will lead to significant changes on the one hand in the field of the delivery of medical bio-materials, drugs and genes and on the other hand in the area of cell- and tissue-engineering.

American start-up for chitosan wound care solutions PhD students in Maryland (University of Maryland and Robert H. Smith School of Business) found their own start-up to develop blood-clotting products. Already two products are in a development phase. A surgical spray and a sponge, both based on chitosan.

Dr. Thomas Freier

Tissue engineering is a rapidly growing interdisciplinary field of research focused on the development of vital autologous tissue through the use of a combination of biomaterials, cells, and bioactive molecules, for the purposes of repairing damaged or diseased tissue and organs. The future tissue engineering market potential has been estimated at 70 billion Euro. Due to its biocompatibility and biodegradability, together with its specific interactions with components of the extracellular matrix and growth factors, chitosan has emerged as exceptionally promising material for various tissue engineering applications, including skin, nerve, bone, and cartilage repair applications.

Have a look at published papers in march 2009.

Do you have an idea for a specific chitin or chitosan product, or have you developed a new derivative? We can make you an offer to manufacture your product on our premises. There are a number of advantages in letting us do the production:

Heppe Medical Chitosan produces not only classical chitins and chitosans but also derivatives of these groups of substances.
Chitosan derivatives are obtained by chemical modification of the reactive chitosan groups (OH-, NH2-).
They have the advantage of possessing the unique pharmacological properties of chitosan, such as

• Anti-bacterial
• Anti-viral
• Hemostatic
• Anti-inflammatory

but at the same time are water soluble. As a result, chitosan derivatives exhibit improved biocompatibility, bioactivity, biodegradability and reduced toxicity. Due to the improved physical and chemical properties, there are extended application possibilities.

Examples of biomedical applications include:

• Medical materials (e.g. wound dressings).
• Nanomaterials e.g. nanoparticles, hydrogels, microspheres
• Drug delivery systems
• Vaccine adjuvants
• Tissue engineering

CHITOSAN DERIVATIVES AT HMC

Our standard range of chitosan derivatives includes:

• Chitosan HCl (in various specification)
• Chitosan glutamate
• Carboxymethyl chitosan
• Chitosan lactate
• Chitosan acetate

In our shop you can directly buy small quantities of chitosan derivatives. For a detailed offer please contact the This email address is being protected from spambots. You need JavaScript enabled to view it. of Heppe Medical Chitosan GmbH. Are you looking for another chitosan derivative? Contact us - we also manufacture on a contract basis.

Due to their different degrees of deacetylation and molecular weights, chitosans are a large group of substances with different properties. In the following, we would like to introduce our product portfolio and show you the broad range of chitosan and its applications.

Christian Augsten, Karsten Mäder

Flow Field-Flow Fractionation (Flow-FFF) is a powerful tool to separate molecules and particles in a range from 103 to 107Da and particles of nanometric size up to a few micrometers [1]. By coupling FFF to Multi-angle light scattering (MALS) it is possible to determine absolute molar masses (M) of molecules and to verify their aggregation. For macromolecules of an appropriate size the radius of gyration (rg) can be achieved [2]. The aim of our study was to investigate various chitosan types by applying Flow-FFF and MALS to their aqueous solutions.

Christian Augsten, Karsten Mäder

Flow Field-Flow Fractionation (Flow-FFF) is a powerful tool to separate molecules and particles in a range from 103 to 107Da and particles of nanometric size up to a few micrometers [1]. By coupling FFF to Multi-angle light scattering (MALS) it is possible to determine absolute molar masses (M) of molecules and to verify their aggregation. For macromolecules of an appropriate size the radius of gyration (rg) can be achieved [2]. The aim of our study was to investigate various chitosan types by applying Flow-FFF and MALS to their aqueous solutions.