Products and service

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Chitosan Derivatives

In addition to classic chitins and chitosans, Heppe Medical Chitosan also produces derivatives of this material group. Our standard chitosan derivatives are Chitosan HCI (in various specifications), Carboxymethylchitosan, Chitosan Lactate, Chitosan Acetate and Chitosan Glutamate.

The advantage of these derivatives is that they are soluble in water and no additional acids need to be added. For all of our products we can make special product specifications for you.

Do you need an offer? Please contact us.

Chitosan HCl

  • also known as Chitosan hydrochloride, Chitosan chloride, Chitosani hydrochloridum
  • listed in Eur. Ph., suitable for medical applications
  • quality according to Eur. Ph.
  • soluble in water
  • Molecular formula: H-(C8-H13-N-O5)n-H-O(C6H11-N-O4)n CL-H

In 2017 we have deversified our product range for chitosan HCl. Now we provide different specifications for degree of deacetylation and viscosity /molecular weight. Also high molecular weight chitosan chloride is now available. For an overview please see the following table. Minimum order size for product 44001 is 20gram. For 54047, 54039, 54040 and 54046 the minimum order quantity is 10gram.

These are our Chitosan HCL standard products:

Chitoceuticals® Chitosan HCl Article numbers
Parameter 44001 54040 54047 54039 54046
Degree of Deacetylation [%] 80-95 75-90 >90 75-90 >90
Viscosity [mPas] 2-200 <20 <20 20-200 20-200
Molecular weight appr. [kDa] 30-200 <300 <300 200-800 200-800
Chloride content [%] 10-20 10-20 10-20 10-20 10-20
pH 4-6 4-6 4-6 4-6 4-6
Ash content [%] ≤ 1 ≤ 1 ≤ 1 ≤ 1 ≤ 1
Protein content [%] ≤ 0.3 ≤ 0.3 ≤ 0.3 ≤ 0.3 ≤ 0.3
Microbiological tests          
  Total bacterial count [cfu/g] ≤ 1000 ≤ 1000 ≤ 1000 ≤ 1000 ≤ 1000
  Yeast and Mould ≤ 100 ≤ 1000 ≤ 1000 ≤ 1000 ≤ 1000
Heavy Metals [ppm]          
  Pb ≤ 10 ≤ 10 ≤ 10 ≤ 10 ≤ 10
  Hg ≤ 1 ≤ 1 ≤ 1 ≤ 1 ≤ 1

Of course we offer also GMP compliant grades with a low bioburden and endotoxin content. The following Chitoceuticals GMP compliant grades are produced in cleanrooms according to EU-GMP guidelines. Minimum order quantity 10 gram. If you need a quotation please do not hesitate to contact us. At the moment our GMP compliant grades are not yet available in the web shop.

Chitoceuticals®
GMP compliant Chitosan HCl
Article numbers
Parameter 55040 55047 55039 55046
Degree of Deacetylation [%] 75-90 >90 75-90 >90
Viscosity [mPa-s] <20 <20 20-200 20-200
Molecular weight appr. [kDa] <300 <300 200-800 200-800
Chloride content [%] 10-20 10-20 10-20 10-20
pH 4-6 4-6 4-6 4-6
Ash content [%] ≤ 1 ≤ 1 ≤ 1 ≤ 1
Protein content [%] ≤ 0.3 ≤ 0.3 ≤ 0.3 ≤ 0.3
Microbiological tests        
  Total bacterial count [cfu/g] ≤ 100 ≤ 100 ≤ 100 ≤ 100
  Yeast and Mould ≤ 100 ≤ 100 ≤ 100 ≤ 100
  E.coli [cfu/g] absent absent absent absent
  P.aeruginosa [cfu/g] absent absent absent absent
  St. Aureus [cfu/g] absent absent absent absent
  Salmonella [cfu/g] absent absent absent absent
Endotoxins [EU/g] ≤ 100 ≤ 100 ≤ 100 ≤ 100
Heavy Metals [ppm]        
  Pb ≤ 10 ≤ 10 ≤ 10 ≤ 10
  Hg ≤ 1 ≤ 1 ≤ 1 ≤ 1

Carboxymethylchitosan

  • example of application: treatment of wounds
  • soluble in water

Chitosan Lactat

  • odourless
  • preferred use in cosmetic applications
  • soluble in water

Chitosan Acetat

  • possible field of application: wound dressing used for burnings
  • soluble in water

Chitosan Glutamate

  • application mainly in the following pharmaceutical fields:
    • drug delivery
    • enhancement of absorption abilities of APIs
    • Tissue Engineering
    • Enhancement of a

Buy chitosan derivatives

In our Onlineshop you can purchase small amounts of chitosan derivatives. Do you need a specific derivative? Or are you looking for a detailed offer? Don't hesitate to contact the Sales department of Heppe Medical Chitosan. You need another derivative? Address us your request - we also offer custom manufacturing.

 

Congress and fairs

Meet us in person:

  • European Chitin Conference, 2017 May 31st - June 3rd, Seville, Spain
  • CPhI, 2017, October 24th - 26th, Frankfurt, Germany
  • MEDICA, 2017, November, 13rd - 16th, Düsseldorf, Germany

To arrange an appointment please contact Katja Richter via sales(a)medical-chitosan.com

Contact

  • Heppe Medical Chitosan GmbH
    Heinrich-Damerow-Strasse 1
    06120 Halle (Saale)
    Germany
  • Tel.: +49 (0) 345 27 996 300
    Fax: +49 (0) 345 27 996 378
  • sales@medical-chitosan.com