In this rubric we present you scientific news from the world of chitin and chitosan. Monthly you can find recent publications. We hope to arouse your interest in this biopolymer or to help you out. If you have any comments or if you do chitin or chitosan research and you want to publish your article on this page,
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Chitosan shows great potential as part of drug release systems of orally administered drug formulations. Another interesting use is as an antigen platform for vaccines. We present an article in which pneumococcal membrane protein-loaded chitosan capsules were prepared and evaluated for their efficacy for a nasally administered vaccine.
Chitosan is already being used in many ways in the pharmaceutical, medical and food industries. A less explored field of application is forensics, for example to make fingerprints visible. In the following article we would like to present a study in which the unique properties of chitosan coupled with lysine are used as a powder to visualize latent fingerprints on glass and rubber surfaces.
The importance of antibiotics remains undiminished today. However, antibiotic resistance is increasing and few new agents are being discovered that can bypass them. In the following article, a chitosan-based nanomaterial was therefore developed that exploits the antimicrobial effect of chitosan to eliminate Salmonella typhimurium.
Due to its biocompatibility and ability to increase the water solubility of drugs, chitosan can be used as an excipient in drug delivery systems. In the following article, we present the influence of physical mixtures of the beta-blocker carvediol (CVD) and chitosan on CVD solubility and release profile.
Biocompatibility, biodegradability and stability are important properties for tissue matrices. At the same time, the material should promote cell attachment, proliferation, differentiation and migration. Besides polylactide, collagen or hyaluronic acid, chitosan can also be used as a biopolymer in tissue engineering. In the presented study, chitosan was functionalized with short peptide sequences as a scaffold for osteoblasts for bone tissue regeneration in order to improve the cellular properties.
chitosan, scaffold, tissue engineering, bone tissue engineering
The development of nanotechnology has opened up new applications in the field of biomedicine. Chitosan and its derivatives can be used in a variety of ways, for example to enable targeted and sustained drug release. To give you an overview, we present a review that deals with the current research on the application of chitosan and its derivatives, especially carboxymthylchitosan (CMC), in biomedicine.