nanoparticles

  • Water-soluble drug release by chitosan microparticles

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    Chitosan and chitosan derivatives are promising biopolymers for nasal or vaginal drug delivery using micro- or nanoparticles. However, the pH-dependent solubility of chitosan and excessive water uptake in the presence of ions is suboptimal. Water uptake can result in rapid initial release of the drug due to collapse of the chitosan-based transport vehicle. To stabilize the drug release, research is being conducted to modify the polymer structure by physical crosslinking. Aim of the presented study was to investigate the influence of microparticle composition, in particular the amount of ion crosslinker (CF) introduced, on the release profile of water-soluble drugs from the chitosan matrix.

     Read more: Water-soluble drug release by chitosan microparticles

  • Chitosan and curcumin for treatment of glaucoma or cancer

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    Glaucoma is a group of diseases of the eye with damaged optic nerve and retina in advanced stages, possibly leading to blindness. One of the causes is increased intraocular pressure. Here, we present two publications, which investigated the combination of chitosan and curcumin for treatment of glaucoma and cancer patients.

     Read more: Chitosan and curcumin for treatment of glaucoma or cancer

  • Chitosan implants for regenerative medicine

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    In recent decades, there have been major advances in regenerative medicine, such as the treatment of severe nerve injuries. Implants used as scaffolds for nerve cell regeneration are often made of biodegradable polymers, such as chitosan. Below, we present a study that investigated the degradation and stability of tubular chitosan-based implants.

     Read more: Chitosan implants for regenerative medicine

  • Respirators with chitosan nanoparticles as protection against SARS-CoV-2 infection

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    In the current corona pandemic, the protection of medical personnel who have contact with Covid-19 infected patients is important, also to ensure stability of the health care services. The personal protective equipment of hospital staff includes particle filtering respiratory masks. From early 2021, a clinical study will be conducted to investigate the protective effect of a new type of respirator with a filter element containing chitosan nanoparticles in Brazil. More about this study and other current clinical studies with chitosan in this article.

     Read more: Respirators with chitosan nanoparticles as protection against SARS-CoV-2 infection

  • Chitosan for pulmonary applications

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    Chitosan is a promising drug delivery system for pulmonary applications and is therefore of particular interest for vaccine development in the Corona Pandemic. The biodegradable and biocompatible polymer's mucoadhesive, permeation-increasing and site-/cell-specific properties are useful in this context. Nanocarriers based on various microencapsulation and micro-nano mixing systems have already been developed. The aerodynamic character is important to enable efficient pulmonary aerosol formation and inhalation. In this article we present research on chitosan as pulmonary particulate anti-infective drug carrier.

     Read more: Chitosan for pulmonary applications

  • Chitosan nanoparticles - potential drug delivery systems for COVID-19 drugs

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    Chitosan nanoparticles can deliver drugs to their specific target site and release them over a long period. In current corona crisis, chitosan nanoparticles could be one way to release potential COVID-19 drugs specifically in the lungs of affected patients. A potential drug delivery system for the treatment of SARS-CoV-2 infected persons is Novochizol™, consisting of chitosan-based nanoparticles.

     Read more: Chitosan nanoparticles - potential drug delivery systems for COVID-19 drugs

  • Chitosan as adjuvant for vaccines

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    Adjuvants in vaccines are potent enhancers, which ensure that even small amounts of pathogens induce a permanent immune response. They are particularly necessary for inactivated vaccines and vaccines with antigen subunits. Several studies investigated chitosan as an adjuvant or antigen delivery system in various formulations (gels, aqueous dispersion, micro- and nanoparticles).

     Read more: Chitosan as adjuvant for vaccines

  • Gold nanoparticles with chitosan

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    There are many potential applications of gold nanoparticles in medicine. Gold nanoparticles are already being used in diagnostics, as in pregnancy or HIV tests [1]. Research on the use as a contrast agent for the localization of cancer cells and as a drug delivery system for targeted release at site of action. The surface properties of gold are optimal for functionalization, e.g. with chitosan.

     Read more: Gold nanoparticles with chitosan

  • Chitosan Research in 2018

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    Also in 2018, scientists around the world have been feverishly researching chitosan in a variety of applications. Often involved is chitosan of highest quality, produced by Heppe Medical Chitosan. At the end of the year, we would like to present articles in which HMC Chitosan has been researched for removal of drugs in water and antibacterial action.

     Read more: Chitosan Research in 2018

  • Publications with chitosan and chitosan derivatives by HMC in 2018

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    Worldwide, our chitosan and chitosan derivatives are used in research. We created a list of scientific articles published in 2018 using chitosan from HMC. Nanoparticles from chitosan or chitosan derivatives were most frequently produced and tested for a wide variety of applications, mainly directed drug delivery and tissue engineering. Curious where to find chitosan by HMC in research?

     Read more: Publications with chitosan and chitosan derivatives by HMC in 2018

  • The world of chitosan in 2016 & chitosan as adjuvant in vaccines

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    At the end of the year we want to give you an overview about chitosan-related publications in 2016 and in the second part we focus on a quite different application of chitosan – how human and veterinary vaccines could benefit from chitosan as adjuvant.

     Read more: The world of chitosan in 2016 & chitosan as adjuvant in vaccines

  • Publications in July & August 2016 - drug delivery systems

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    Today´s topic is chitosan for drug delivery systems. In July and August 2016, 33 articles about chitosan combined with drug delivery systems were published. As might be expected, top publisher are China (13 articles), United States (5) and India (4). The articles investigated drug release by chitosan-based micro- or nanoparticles, hydrogels and nanocomposites. Thereby controlled release of cytostatics, proteins or peptides was mainly studied. (Source: www.gopubmed.org)

     Read more: Publications in July & August 2016 - drug delivery systems

  • Publications in Febuary 2016

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    70 Publications with the chitosan topic were published in Febuary. In the ranking of nations China (14) was on the first place, followed by Iran (8) and India (8). Scientific Report – Nature published the article of Kamat V. et al. from Agharkar Research Institute in India.

     Read more: Publications in Febuary 2016

  • Publications in January 2016

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    In January were 77 publications with chitosan topics published. In addition to China (26) and the United States (11), Egypt (6) is on the third place of nations with the most publications.

     Read more: Publications in January 2016

  • Publications in April 2015

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    In April 139 publications have been released about chitosan, which mainly focused on topics like evaluation studies, pharmaceutical preparations and nanoparticles. The leading nations in the field of chitosan research are China (48 articles), India (18) and USA (13).

     Read more: Publications in April 2015

  • Publications in September and October 2013

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    In September and October 2013, 290 publications about chitosan and its diverse derivatives have been released. They present novel formulations of chitosan-based nanoparticles and pharmaceutical preparations and performed animal and human studies. The leading nations in chitosan research are China (75 articles), India (37) and USA (27).

     Read more: Publications in September and October 2013

  • Publication May and June 2013

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    231 articles about chitosan and chitosan derivatives have been published in May and June 2013. The main topics focused on animal and human studies and on chitosan-based nanoparticles and pharmaceutical preparations. Moreover, the physico-chemical properties and pH sensitivity of various chitosan derivatives were intensively studied. Among the top nations of chitosan research are again: China (76 articles), USA (30) and India (14).

     Read more: Publication May and June 2013

  • Publications in November & December 2014

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    At the end of the year 2014 numerous articles about chitosan and chitosan derivatives were published.  All in all 312 reports were released in November and December by leading scientists from China (89 articles), USA (35) India (28) and South Korea (21).

     Read more: Publications in November & December 2014

  • Publications in May & June 2014

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    In the mid-year, 227 articles have been released about chitosan. The main topics addressed nanoparticles, pharmaceutical preparations, evaluation studies, animals and humans. The leading nations in publishing chitosan-related articles are again China (69 articles), USA (28) and India (21). German scientists published 5 reports.

     Read more: Publications in May & June 2014

  • Publications in January and February 2014

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    At the beginning of 2014, a variety of highly interesting chitosan-related articles were released by scientists from all over the world. All in all, 281 novel articles have been published, which promise new insights into the diversity of the biopolymer. The most successful nations in the field of chitosan research are again China publishing 88 articles, USA 33 reports and India contributed 23 articles.

     Read more: Publications in January and February 2014

  • Publications in March 2015

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    In March 2015, 201 articles about chitosan and chitosan derivatives have been published. The main topics address chitosan in evaluation studies, nanoparticles, pharmaceutical preparations and tissues. Among the top countries of chitosan research are again: China (51 articles), India (23) and USA (21).

     Read more: Publications in March 2015

  • Publications in February 2015

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    After an excellent start in January 2015, the number of chitosan-related articles slightly decreased in February. Scientific journals released 142 publications, which mainly focused on pharmaceutical preparations, nanoparticles and evaluation studies. Again, the three leading nations in chitosan research are China (40 articles), India (19) and USA (13). German scientists are placed among the top 10, as they contributed 5 reports.

     Read more: Publications in February 2015

  • Publications in January 2015

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    At the beginning of the year 2015, an incredible large number of chitosan-related articles have been released, indicating another record year. All in all, 196 publications about chitosan and its derivatives were contributed by scientist from all over the world, especially from China (46 articles), India (29) and USA (15). The main terms address chitosan in evaluation studies, nanoparticles and pharmaceutical preparations. 

     Read more: Publications in January 2015

  • Publications in March and April 2013

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    In March and April 262 publications were released about Chitosan, which mainly focused on animal and human studies, nanoparticles and pharmaceutical preparations. The most successful nations in the field of chitosan research have been: China (83 articles), India (31) and USA (22).

     Read more: Publications in March and April 2013

  • The antimicrobial and skin regenerative effect of chitosan-based nanoparticles

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    The antimicrobial effect of chitosan is well known and has already been used in dentistry to prevent caries as well as in the food packaging industry as a preservative agent.

     Read more: The antimicrobial and skin regenerative effect of chitosan-based nanoparticles

  • Publications in March 2012

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    Overall 131 articles about chitosan and chitosan derivatives were published in March 2012.

    As in the previous month, China is the country with the most publications with overall 35 articles, followed by the USA (14 articles), India (9 articles) and Taiwan (8 articles).

     

     Read more: Publications in March 2012

  • Publications January 2012

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    January opens the publication year 2012 with overall 159 articles about chitosan. Almost one third of the articles was published in China.


    China:    56 articles
    India:    15 articles
    USA:     14 articles
    Tawain:   7 articles 
     

     Read more: Publications January 2012

  • Publications in September 2011

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    In September a total of 62 articles were published in the field of chitosan. In this month the most publications came from China where 10 articles were published. With 7 articles India was in second place followed by the USA where 6 articles were published.

     Read more: Publications in September 2011

  • Publications in February 2011

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    In the februar of this year 81 papers about chitosan and its derivates were published. As in the months before also in February china was with 21 publications the most active country in this field of research followed by the USA with 12 publications and India with 4.

     Read more: Publications in February 2011

  • Publications in January 2011

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    Starting in a new year in January 2011 92 articles about chitosan and its derivates were published. The top themes in the last month were evaluation studies, studies in tissues and about nanoparticle with 26, 25 and 21 publications.

     Read more: Publications in January 2011

  • Publications in December 2010

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    In December 2010 116 articles dealing with chitosan or chitosan derivates were published. With 31 publications about chitosan China is the country which publicized the most ones followed by USA with 10 publications and India with 9. There chitosan nanoparticles, evaluation studies and pharmaceutical preparations were of most interest (37, 34 and 33 publications).

     Read more: Publications in December 2010

  • Novel synthesis of nanocomposites with chitin

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    Bruno Alonso and Emmanuel Belamie of the Charles Gerhardt Institute in Montpellier, France developed a new large-scale synthesis of bioorganic-inorganic nanocomposites: self-organising chitin-silicon dioxide nanocomposites with unpredecented specificity in texture and structure of the product.

     Read more: Novel synthesis of nanocomposites with chitin

  • Nanoparticles: Trojan Horse for APIs

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    The big challenge in the field of medical innovations is so tiny that it is not noticeable with the naked eye. Nanotechnology – a promising and trendsetting technology. For example, with the help of drug-delivery-systems drugs can be transported to an exactly defined part within the body.
    Chitosan also produces nanoparticles.

     Read more: Nanoparticles: Trojan Horse for APIs

  • Veröffentlichungen im August 2010

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    Der Sommer neigt sich zum Ende – das heißt aber nicht, dass die News rund um Chitosan nicht heiß sind. Hier der Review der Chitosan Veröffentlichungen im August. 97 wissenschaftliche Artikel wurden veröffentlicht, in denen mit Chitosan gearbeitet wurde. Im Int J Biol Macromol wurden 8 Artikel veröffentlicht. Die Top drei Nationen bezogen auf die Anzahl der Artikel sind China, USA und Indien, gefolgt von Portugal auf Platz 4.

     Read more: Veröffentlichungen im August 2010

  • Publications in July 2010

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    In July several outstanding articles about chitosan had been published around the world.  All in all 122 articles were released in 67 different journals. With regard to the number of publications the leading countries are China (31), the USA (20) and South Korea (10).

     Read more: Publications in July 2010

  • Chitosan in biocompatible fuel cells

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    Chitosan is employed in many domains. Besides medical areas like e.g. as support in wound healing or in tissue engineering chitosan can also be applied in the fields of food technology and water management. Thanks to scientists of the faculty of Microsystems Technic at the Univesity of Stuttgart, chitosan might soon become part of biocompatible fuel cells.

     Read more: Chitosan in biocompatible fuel cells

  • Current articles about chitosannanoparticles

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    In the first two months of this year numerous articles about chitosannanoparticles has been published into the following journals: biomaterials [6],  biomed mater res a [2], j mater sci-mater m [2], langmuir [2], biomacromolecules [2]. The Authors are from Asia, Europe and Northamerica.

     Read more: Current articles about chitosannanoparticles

  • Chitosan a Panacea? - NanoBioSaccharides brightens the dark

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    Chitosan - NanoBioSaccharides brightens up the darkNanoBioSaccharides - a project that aimed to unravel the properties of an apparent panacea is now concluded. During the last three years over 600 researchers from seven nations, managed by Prof. Dr. Bruno Moerschbacher of the University of Muenster dedicated their time to study the striking abilities of Chitosan and its application in human medicine. In Nanobiotechnology a breakthrough is expected, that will lead to significant changes on the one hand in the field of the delivery of medical bio-materials, drugs and genes and on the other hand in the area of cell- and tissue-engineering.

     Read more: Chitosan a Panacea? - NanoBioSaccharides brightens the dark

Congress and fairs

Meet us in person 2022:

  • EUCHIS, 2022
  • CPHI 2022
  • Medica 2022
  • Asia Pacific Chitin and Chitosan Symposium, 2022, South Korea

To arrange an appointment please contact Katja Richter via sales(at)medical-chitosan.com

Contact

  • Heppe Medical Chitosan GmbH
    Heinrich-Damerow-Strasse 1
    06120 Halle (Saale)
    Germany
  • Tel.: +49 (0) 345 27 996 300
    Fax: +49 (0) 345 27 996 378
  • sales@medical-chitosan.com

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