In this rubric we present you scientific news from the world of chitin and chitosan. Monthly you can find recent publications. We hope to arouse your interest in this biopolymer or to help you out. If you have any comments or if you do chitin or chitosan research and you want to publish your article on this page,
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Around one third of all type-2 diabetes sufferers develop diabetic foot ulcers in the course of their disease. Due to biofilm formation and multi-resistant bacteria, inflammation occurs in 50% of those affected. This article presents a study investigating the treatment of these with chitosan-containing metallic nanoparticles coupled to toluidine blue as a photosensitizer.
A large number of reviews on Chitosan were also published in 2021. According to HMC searches in the PubMed database, a total of 181 new reviews with chitosan in the title appeared in 2021. In this article, we would like to give you an overview of the publications, as well as briefly introduce five reviews on various topics related to chitosan. Have fun reading!
Various polysaccharides such as chitosan and β-glucan possess immunological properties that are advantageous for vaccine adjuvants. Therefore, in the presented study, chitosan and carboxymethyl-β-glucan were combined as nanoparticles, coupled to the model antigen ovalbumin as vaccine adjuvant and investigated in vivo in a mouse model.
chitosan, nanoparticles, vaccine, carboxymethylchitosan, antigen
The global corona pandemic requires effective vaccines to achieve herd immunity. In the study presented here, an inhalable chitosan-based nanovaccine containing the viral spike protein (S) was developed to specifically induce immunity at the mucosal sites of the respiratory tract.
Electrophoretic deposition is getting more attention in recent years. It is cost-effective and can be applied in many ways to produce a variety of composites. In the following, we present an article highlighting the influence of initial concentrations and process parameters on the deposition of chitosan-hydroxyapatite structures. Furthermore, the bonds and interactions in the deposited structures were also investigated.
Chronic, painful diseases such as endometriosis can lead to a severe reduction in the quality of life of those affected. Drug delivery systems, such as chitosan-containing hydrogels, could enable efficient pain management with prolonged and targeted drug release. Therefore, in the study presented here, hydrogels made of chitosan and the vanillin derivative 2-hydroxy-5-nitrobenzaldehyde were investigated as a drug delivery system for diclofenac sodium salt.