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Orthopedic infections can be treated with antibiotic-loaded bone cements. However, due to the growing number of resistances, new formulations are needed to e.g. improve the drug release. For this reason, dual-antibiotic bone cement containing chitosan and chitosan oligosaccharide was prepared in the presented study.
infection, bone cements, chitosan oligomer, antibiotics, biocompatibility
As the population ages, the number of Alzheimer's cases could triple by 2050. To enable early diagnosis, sensitive and easy-to-use diagnostic platforms are needed. Therefore, in the presented study, an electrochemical immunosensor was fabricated using chitosan and gold nanoparticles functionalized carbon nanotubes.
Chronic wounds represent a major burden on the quality of life of those affected. To improve their situation, multilayer films of chitosan, alginate and the fibroblast growth factor FGF2 were prepared in the presented study and their potential as wound dressings was investigated.
chitosan, wound treatment, wound dressing, antibacterial, layer-by-layer
On November 16, 2022 the supporting association of the new cluster initiative Life-Science Saxony-Anhalt was founded in the technology park Weinberg Campus. We, the Heppe Medical Chitosan GmbH, are excited to be part of it as a founding member.
Injuries to the peripheral nervous system can cause substantial motor and sensory deficits. In the presented study, self-assembling peptide-based hydrogels are injected into a chitosan nanofiber scaffold and used as an artificial nerve graft.
Chronic wounds affect 1-2% of the population. In the presented study, chitosan-coated and chitosan-containing liposomes were prepared to enhance the antibacterial effect of the drug chlorhexixdine. A chitosan-based delivery system enhances the antimicrobial activity of chlorhexidine.