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Electrophoretic deposition is getting more attention in recent years. It is cost-effective and can be applied in many ways to produce a variety of composites. In the following, we present an article highlighting the influence of initial concentrations and process parameters on the deposition of chitosan-hydroxyapatite structures. Furthermore, the bonds and interactions in the deposited structures were also investigated.
Chronic, painful diseases such as endometriosis can lead to a severe reduction in the quality of life of those affected. Drug delivery systems, such as chitosan-containing hydrogels, could enable efficient pain management with prolonged and targeted drug release. Therefore, in the study presented here, hydrogels made of chitosan and the vanillin derivative 2-hydroxy-5-nitrobenzaldehyde were investigated as a drug delivery system for diclofenac sodium salt.
Chitosan shows great potential as part of drug release systems of orally administered drug formulations. Another interesting use is as an antigen platform for vaccines. We present an article in which pneumococcal membrane protein-loaded chitosan capsules were prepared and evaluated for their efficacy for a nasally administered vaccine.
Chitosan is already being used in many ways in the pharmaceutical, medical and food industries. A less explored field of application is forensics, for example to make fingerprints visible. In the following article we would like to present a study in which the unique properties of chitosan coupled with lysine are used as a powder to visualize latent fingerprints on glass and rubber surfaces.
The importance of antibiotics remains undiminished today. However, antibiotic resistance is increasing and few new agents are being discovered that can bypass them. In the following article, a chitosan-based nanomaterial was therefore developed that exploits the antimicrobial effect of chitosan to eliminate Salmonella typhimurium.
Due to its biocompatibility and ability to increase the water solubility of drugs, chitosan can be used as an excipient in drug delivery systems. In the following article, we present the influence of physical mixtures of the beta-blocker carvediol (CVD) and chitosan on CVD solubility and release profile.