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The treatment of complex bone defects, particularly in the cranio-maxillofacial region, remains a major clinical challenge. Autologous grafts are considered the gold standard, but they are associated with limitations such as resorption, insufficient fit, and infection risks.
Dopamine is one of the most important neurotransmitters in the human brain. Its imbalance is associated with neurological disorders such as Parkinson’s disease, schizophrenia, or Huntington’s disease.
Radiotherapy remains one of the main pillars of modern cancer treatment. However, despite advances in precision targeting, damage to surrounding healthy tissue continues to pose a significant clinical problem - especially in thoracic malignancies. In such cases, the lungs represent a particularly radiosensitive organ.
Chitosan is no longer just an interesting biopolymer for the food or wound healing sectors. It is gaining attention in many other fields as well – particularly due to its radical scavenging, hematopoietic, and cytoprotective properties. One of the most promising areas of application: radioprotection, i.e., the protection of tissue from damage caused by ionizing radiation.
Chitosan is a versatile biopolymer that is gaining increasing importance in the food and packaging sectors. With its antimicrobial properties, biodegradability, and film-forming capacity, it offers sustainable solutions for shelf-life extension and plastic-free packaging. However, its effectiveness is not determined by degree of deacetylation (DDA) and molecular weight (MW) alone – rather, it results from a combination of chemical and physical characteristics that determine its suitability for different applications.
Treating infected burn wounds - especially those involving antibiotic-resistant bacteria - remains a major challenge in modern medicine. A research team has now introduced a groundbreaking solution: a hydrogel-based microneedle system that combines so-called “high-entropy nanozymes” with chitosan.
This novel technology not only combats resistant pathogens but also actively promotes wound healing—with a special focus on chitosan’s role as a key material.