Crosslinking

Improved chitosan nerve conduits through crosslinking
Artificially produced nerve conduits are promising alternatives to autologous nerve grafts in the treatment of damaged nerves. In this study, the physiochemical properties of chitosan/poly-ε-caprolactone nerve conduits will be improved by using the chitosan crosslinker genipin.

Bimetallic chitosan microgels
The use of microgels is one way of biomimetically mimicking tissue. In the presented study, chitosan microgels will be functionalized with Zn (II) and Cu (II) ions to improve their physicochemical properties.

Influence of crosslinkers and stabilization methods on porous chitosan-bioglass networks
Chitosan bioglass networks can be used as biomaterials in medicine, for example, as bone implants. Their physiochemical and mechanical properties can be improved by crosslinkers and various stabilization methods. In the presented study, six of them were compared with each other.

Antibacterial, multifunctional hydrogel based on carboxymethylchitosan
Hydrogels can have versatile applications in biomedicine by forming a 3D network. In the study presented here, an antibacterial, adhesive, self-repairing hydrogel was prepared from carboxymethylchitosan (CMC) and oligomeric polycyanidin (OPC) and the influence of OPC content was investigated.

Wound treatment with chitosan
The healing process of a wound injury follows the steps of hemostasis, inflammation, cell proliferation, and regeneration until complete healing of the damaged tissue. In chronic wounds, the progress of these steps is disturbed, leaving the wounds inflamed for a long time. In an aging society with bad health habits (poor diet, little exercise), the number of chronic wounds is going to increase. Therefore, the research on materials that improve wound healing is important. The publications presented below are devoted to research about chitosan-based materials for the treatment of chronic wounds.

Publications in September & October 2014
In September and October, 276 chitosan-related articles have been released. The main topics addressed chitosan in evaluation studies, pharmaceutical preparations, nanoparticles and tissue engineering. The highest number of publications was performed by the leading nations China (73 articles), USA (28) and India (22). German scientists published 8 articles, placing them in the top-ten list.

Publications in May & June 2014
In the mid-year, 227 articles have been released about chitosan. The main topics addressed nanoparticles, pharmaceutical preparations, evaluation studies, animals and humans. The leading nations in publishing chitosan-related articles are again China (69 articles), USA (28) and India (21). German scientists published 5 reports.