Current clinical studies with chitosan
Clinical studies serve evidence-based medicine and enable the development and application of new, innovative medical products and drugs. At the moment, there are several clinical studies with chitosan-containing products or devices, for example, in relation to wound healing, tumor detection or Covid-19. In this article, we would like to give you an overview of the ongoing studies.
Currently, 20 clinical trials related to chitosan with the status 'recruiting' and 'not yet recruiting' can be found on https://www.clinicaltrials.gov/ (as of June 14, 2022). This is twice as many compared to 2020 and 2018.
The table below provides an overview of ongoing studies in terms of title, disease, medical intervention/device, status, and study location.
|
Title
|
Condition
|
Intervention
|
Status
|
Location
|
|
|
1 |
Efficacy and Safety of Sericin and Chitosan Cream for Preventing and Limiting the Progressive of Pressure Sore
|
Pressure Ulcer
|
Other: sericin and chitosan cream
|
Recruiting
|
Bangkok, Thailand
|
|
2 |
Long-term Safety and Performance of KiOmedine CM-Chitosan Supplementation in Advanced Symptomatic Knee Osteoarthritis
|
Osteoarthritis, Knee
|
Device: KiOmedine® CM-Chitosan
Device: Synvisc-One®
|
Recruiting
|
Ghent, Belgium
|
|
3 |
The Effectiveness of Antibacterial Therapeutic Clothing Based on Silver or Chitosan as Compared with Non-antibacterial Therapeutic Clothing in Patients with Moderate to Severe Atopic Dermatitis
|
Atopic Dermatitis
|
Device: DermaCura® Chitosan based antimicrobial therapeutic clothing
Device: Binamed® silver based antimicrobial therapeutic clothing
Device: Binamed® therapeutic clothing without antimicrobial agents
|
Recruiting
|
Rotterdam, Netherlands
|
|
4 |
MicroFIBERgut: Effects of Lifestyle Changes and Chitosan on Gut Microbiota and Weight Management
|
Obesity
Lifestyle
|
Behavioral: Lifestyle changes
Dietary Supplement: Chitosan
Other: Placebo
|
Recruiting
|
Mosfellsbaer, Iceland
|
|
5 |
Effectiveness of a Novel Respirator with Chitosan Nanoparticles
|
Covid19
SARS-CoV Infection
Worker-Patient Transmission, Healthcare
|
Device: VESTA respirator
Device: Conventional N95 respirator
|
Recruiting
|
Brasília, Brazil
|
|
6 |
Metabolic Effect of an Innovative Chitosan Formulation
|
Hypercholesterolemia
Overweight and Obesity
|
Device: Medical Device (Kaptufat®)
Other: Placebo
|
Not yet recruiting
|
Bologna, Italy
|
|
7 |
Evaluation of the Cell Detachment Ratio on pH-responsive Chitosan as a Prognostic Factor in Lung Cancer
|
Clinical Decision-Making
Early Detection of Cancer
|
|
Recruiting
|
Taipei, Taiwan
|
|
8 |
Develop the First Aid Medical Supplies for Hemostasis and Bacteriostasis With Clinical Trial
|
Cesarean Section
|
Device: Regular Gauze
Device: Chitosan Dressing
|
Recruiting
|
Taipei, Taiwan
|
|
9 |
Clinical & Radiographic Evaluation of LSTR in Non-vital Primary Molars Using Two Different Vehicles
|
Resorption of Tooth or Root
|
Drug: Double antibiotic paste mixed with chitosan nanoparticles
Drug: Double antibiotic paste mixed with propylene glycol
|
Not yet recruiting
|
|
|
10 |
SPiT-frequency; the Effect of Increased Frequency of Intervention on Post-surgical Peri-implant Inflammation
|
Peri-Implantitis
|
Other: Submucosal supportive therapy
|
Not yet recruiting
|
|
|
11 |
To Evaluate the Efficacy and Safety of MaxioCel Versus Aquacel Extra for the Management of Chronic Wounds
|
Wound
|
Device: MaxioCel
Device: AquaCel Extra
|
Not yet recruiting
|
Hyderabad, India
Vijayawada, India
|
|
12 |
NOVAPAK Nasal Packing in Shellfish Allergic Patients
|
Shellfish Hypersensitivity
Epistaxis
|
Device: NOVAPAK nasal packing applied to forearm
Device: NOVAPAK nasal packing applied to nasal cavity
|
Not yet recruiting
|
London, Ontario, Canada
|
|
13 |
Combination of InnoSEAL Plus TR Band Compared to TR Band Alone
|
Radial Artery Occlusion
Hematoma
|
Device: InnoSEAL+TRB
Device: TRB alone
|
Recruiting
|
Karachi, Sind, Pakistan
|
|
14 |
A Comparison of JointRep® and Microfracture in Repair of Cartilage Lesions on the Femoral Condyle or Trochlea
|
Chondral Defect
Articular Cartilage Defect
Articular Cartilage Disorder of Knee
|
Device: JointRep®
Procedure: Microfracture
|
Recruiting
|
Kogarah, New South Wales, Australia
Newcastle, New South Wales,
Randwick, New South Wales, Australia
(and 3 more)
|
|
15 |
Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With Advanced Solid Tumors
|
Advanced Solid Tumors
|
Drug: IP-001 Device: Thermal Ablation
|
Recruiting
|
Chur, Switzerland
Lausanne, Switzerland
St. Gallen, Switzerland
|
|
16 |
Efficacy of BST-CarGel in Treating Chondral Lesions of the Hip
|
Disorder of Hip Region
|
Device: BST-CarGel Procedure: Microfracture
|
Not yet recruiting
|
|
|
17 |
Ortho-R® for Rotator Cuff Repair Compared With Standard of Care Rotator Cuff Repair Without Ortho-R®
|
Rotator Cuff Tears
|
Drug: Ortho-R/PRP
|
Not yet recruiting
|
|
|
18 |
Superficial Partial-Thickness Burn Study
|
Superficial Partial Thickness Burn
|
Device: Catasyn™ Advanced Technology Hydrogel and SynePure™ Wound Cleanser
Drug: Silver Sulfadiazine
|
Recruiting
|
Pittsburgh, Pennsylvania, United States
|
|
19 |
Radial Artery Puncture Hemostasis Study
|
Radial Artery Hemostasis
|
Device: Radial artery hemostasis
|
Recruiting
|
Szeged, Csongád-Csanád, Hungary
Debrecen, Hajdú-Bihar, Hungary
Budapest, Hungary
|
|
20 |
P11-4 and Nanosilver Fluoride Varnish in Treatment of White Spot Carious Lesions
|
White Spot Lesion
|
Other: self-assembling peptide
Other: nanosilver fluoride varnish
Other: sodium fluoride varnish
|
Recruiting
|
Alexandria, Egypt
|