Meeting of the Controlled Release Society
Controlled_Release_2010-photo by Steve TerrillThis Year, scientists and experts convened for their annual meeting themed “Personalized Medicines and Products for the Next Generation, in Portland, USA”. For many work groups Chitosan is indispensable for their research.
At the 37th meeting of the Controlled Release Society, members used the opportunity to present their latest findings and developments. Researchers worked with chitosan in the following fields: vaccines, hydrogels, tissue engineering, nanoparticls, biomaterials, blood-brain-barrier technologies, orale absorption and siRNA-Therapy.
Chitosan and chitosan derivatives are the research basis for many scientific teams all over the world. Groups from Korea, Turkey, the Netherlands, Italy, the US, Brazil, Saudi-Arabia, Taiwan, Portugal, Great Britain and Germany showed how they implemented chitosan in their research and development work for controlled release devices.
The following speeches were delivered and posters presented in the above mentioned fields.
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1 Vaccines |
| Conjugation of ovalbumin to trimethyl chitosan improves immunogenicity of the antigen: A strategy for (mucosal) subunit vaccination: |
| Slütter, B., Soema, P., Ding, Z., Verheul,R., Hennink, W., Jiskoot, W.; Leiden University, The Netherlands |
| Comparison of Chitosan-based Gel and Microparticle Formulations for Mucosal Immunization Against Bovine Herpes Virus 1 (BoHV-1): |
| Gunbeyaz, M., Faraji Majarashin, A., Ozkul, A., Purali, N., Senel, S.; Hacettepe University, Turkey |
| N-Trimethyl Chitosan-based Formulations for Intradermal and Transcutaneous Immunization: |
| Bal, S., Ding, Z., Kersten, G., Jiskoot, W., Bouwstra, J.; Leiden University, The Netherlands |
|
2 Hydrogels |
| Photo-crosslinkable Chitosan Hydrogels as a Nerve Adhesive: |
| Amoozgar, Z., Park, J., Rickett, T., Shi, R., Yeo, Y.; Purdue University, USA |
| Bio-molecular Mass Transport Across Alginate Microcapsules with Genipin-Chitosan Membrane Shell:Implications for microbioreactor-based Protein Delivery: |
| Ranganath, S., Tan, A., He, F., Krantz, W., Wang, C.; National University of Singapore, Singapore |
| Controlled release of basic fibroblast growth factor from chitosan/heparin hydrogel: |
| Yoo, H., Choi, J., Kim, H., Son, Y.; Kangwon National University, Korea |
| Ionically Crosslinked Chitosan Gels for Controlled Release of Antibiotics: |
| Rasul, N., Dosanjh, P., Low, W., Kenward, M., Martin, C.; University of Wolverhampton, UK |
| Thermally Sensitive Gels Based on Chitosan for the Treatment of Vaginal Mucositis: |
| Rossi, S., Ferrari, F., Faccendini, A., Sandri, G., Bonferoni, M., Mori, M., Puccio, A., Caramella, C.; University of Pavia, Italy |
|
3 Tissue Engineering |
| Sustained Delivery of Acidic Fibroblast Growth Factor Carried by Chitosan/Heparin nanoparticles Following Spinal Cord Injury: |
| Huang, Y., Hsu, S., Kuo, S., Cheng, H., Huang, Y.; National Taiwan Ocean University, Taiwan |
|
4 Nanoparticles |
| Application and Preparation of Modified Water-soluble Chitosan Nanoparticles: |
| Nah, J., Choi, C., Jang, M.; Sunchon National University, Korea |
| Chitosan/Tripolyphosphate Nanoparticles for Zidovudine Nasal Delivery: |
| Barbi, M., Carvalho,F., Kiill, C., Gremiao, M.; Unesp, Brazil |
| Clobetasol-17-propionate-loaded Lecithin-Chitosan Nanoparticles: Skin Permeation and Histological Evaluation: |
| Senyigit, T., Sonvico, F., Barbieri, S., Tekmen, I., Ozer, O., Santi, P., Colombo, P; Ege University, Turkey |
| Chitosan-modified PLGA nanoparticles for the delivery of telomerase inhibitor 2′-O-methyl-RNA to non-small-cell lung cancer cells and tumors: |
| Loretz, B., Philippi, C., Koerbel, C., Dong, M., Beisner, J., Muerdter, T., Klotz, U., Laschke, M., Menger, M., Schaefer, U., Lehr, C.;Saarland University, Germany |
| Zwitterionic Chitosan as a Potential Stealth Coating Material for Cationic Nanocarriers: |
| Xu, P., Yeo, Y.; Purdue University, USA |
| Nanoparticles Obtained by Chitosan and Oleic or Linoleic Acid Interaction Intended for Wound Healing: Preliminary Evaluation on Fibroblasts: |
| Bonferoni, M., Sandri, G. Timaç, H., Mori, M., Rossi, S., Ferrari, F., Caramella, C.; University of Pavia, Italy |
| 5 Biomaterials |
| Screening of M cell-homing peptide for Peyer’s patch targeting by phage display and validation of its targeting efficiency using chitosan nanoparticles: |
| Cho,C., Yoo, M., Choi, J., Jiang, T., Kang, S., Choi, Y., Lee, S., Park, I., Na, H., Lee, H.; Seoul National University, Korea |
| Biocompatibility of Chitosan Derivatives in Intraperitoneal Administration: |
| Bajaj, G., Yeo, Y.; Purdue University, USA |
| Novel tailorable thiolated trimethylated chitosans for covalently stabilized nanoparticles: |
| Verheul, R., Censi, R., Van Der Wal, S., Hennink, W.;Utrecht University, The Netherlands |
|
6 Blood-Brain-Barrier Technologies |
| Development of an Oligonucleotide Carrier Nanoparticulate System with Modified Chitosan Polymers: |
| Kozlu, S., Capan, Y.; Hacettepe University, Turkey |
|
7 Oral Absorption |
| Effects of Different Polymers on the Drug Release of Zolmitriptan from Sublingual Tablet Formulations: |
| Bayrak, Z., Tas, C., Tasdemir, U., Erol, H., Kose Ozkan, C.,Savaser, A., Ozkan, Y.; Gülhane Military Medicine Academy, Turkey |
| Formulation and in vitro studies of sodium diclofenac from hydrophilic matrix; Vueba: |
| M., Chevreux, A., Pina, M.;University of Coimbra, Portugal |
| A New Theophylline Chronotherapeutic Drug Delivery System for the Treatment of Nocturnal Asthma: |
| Yassin, A., Al-Suwayeh, S., Aodah, A., Taha, E.; King Saud University, Saudi Arabia |
|
8 siRNATherapy |
| Chemical modification of chitosan as si/shRNA gene Carrier: |
| Jiang, H., Kim, Y., Arote, R., Lim, H., Cho, M., Cho, C.; Seoul National University, Korea |
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Further information on the Controlled Release Society are available here.
Source: Controlled Release