Chitosan as excipient against Heliobacter pylori
H. pylori infections in the stomach are difficult to combat due to the formation of antibiotic resistance, biofilms and intracellular infections. In the presented study, a hydrogel platform based on chitosan and palmitic acid will be used as an alternative to antibiotic-based therapy.
Chitosan and chitosan oligosaccharides in antibiotic-loaded bone cement
Orthopedic infections can be treated with antibiotic-loaded bone cements. However, due to the growing number of resistances, new formulations are needed to e.g. improve the drug release. For this reason, dual-antibiotic bone cement containing chitosan and chitosan oligosaccharide was prepared in the presented study.
Publications in March 2017 - antimicrobial activity of chitosan
In March 2017, 215 articles were released about chitosan and chitosan derivatives. The top three nations in chitosan research are China (59), India (32) and USA (27). Main focuses were nanoparticels, evaluation studies and pharmaceutical preparations.