Modification of denture materials with chitosan salts
Fungal infection with Candida of dentures is a common complication. The adhesion of microorganisms such as Candida is influenced by material properties such as surface charge, hydrophobicity and roughness. The formation of oral biofilms is associated with caries, periodontitis or denture stomatitis. It is therefore important to prevent the formation of biofilms, also because antifungal agents are of little help.
The polymer polymethyl methacrylate (PMMA) is widely used for denture fabrication due to its biocompatibility, but it is susceptible to biofilm formation. Therefore, research into strategies to endow dentures with antifungal properties is important.
Recent and ongoing clinical studies with chitosan
Clinical trials are done to investigate if the treatment is efficient and safe, to improve the health and quality of the life for patients. In this article, we present you clinical trials with chitosan-based products which are about to be performed and two completed clinical trials about dental implant maintenance and chitosan nerve tubes.